Publikationen
Hier finden Sie eine Liste der Publikationen, bei denen Mitglieder des BIUM-MZ einen Beitrag leisteten:
- Ludt A, Ustjanzew A, Binder H,
Strauch K, Marini F. Interactive and
Reproducible Workflows for Exploring and Modeling RNA‐seq Data with
pcaExplorer, Ideal, and GeneTonic. Current Protocols. 2022;2(4). doi:10.1002/cpz1.411
- Das Gupta D, Paul C, Samel N, Bieringer M, Staudenraus D,
Marini F, Raifer H, Menke L, Hansal L, Camara B, Roth
E, Daum P, Wanzel M, Mernberger M, Nist A, Bauer UM, Helmprobst F,
Buchholz M, Roth K, Bastian L, Hartmann AM, Baldus C, Ikuta K, Neubauer
A, Burchert A, Jäck HM, Klein M, Bopp T, Stiewe T, Pagenstecher A,
Lohoff M. IRF4 deficiency vulnerates B-cell progeny for leukemogenesis
via somatically acquired Jak3 mutations conferring IL-7
hypersensitivity. Cell Death & Differentiation. Published online
April 22, 2022. doi:10.1038/s41418-022-01005-z
- Kaps L, Huppertsberg A, Choteschovsky N, Klefenz A, Durak F, Schrörs
B, Diken M, Eichler E, Rosigkeit S, Schmitt S, Leps C, Schulze A,
Foerster F, Bockamp E, De Geest BG, Koynov K, Räder HJ,
Tenzer S, Marini F, Schuppan D, Nuhn L. pH-degradable,
bisphosphonate-loaded nanogels attenuate liver fibrosis by
repolarization of M2-type macrophages. Proceedings of the National
Academy of Sciences. 2022;119(12). doi:10.1073/pnas.2122310119
- Nührenberg TG, Stöckle J, Marini F, Zurek M,
Grüning BA, Benes V, Hein L, Neumann FJ, Stratz C, Cederqvist M,
Hochholzer W. Impact of high platelet turnover on the platelet
transcriptome: Results from platelet RNA-sequencing in patients with
sepsis. James K, ed. PLOS ONE. 2022;17(1):e0260222. doi:10.1371/journal.pone.0260222
- Ustjanzew A, Desuki A, Ritzel C, Dolezilek AC, Wagner DC, Christoph
J, Unberath P, Kindler T, Faber J, Marini F, Panholzer
T, Paret C. cbpManager: a web application to streamline the integration
of clinical and genomic data in cBioPortal to support the Molecular
Tumor Board. BMC Medical Informatics and Decision Making. 2021;21(1). doi:10.1186/s12911-021-01719-z
- Marini F, Ludt A, Linke J,
Strauch K. GeneTonic: an R/Bioconductor package for
streamlining the interpretation of RNA-seq data. BMC Bioinformatics.
2021;22(1). doi:10.1186/s12859-021-04461-5
- Paret C, Lehmann N, Bender H, Sprang M, Sommer CJ, Cana D, Seidmann
L, Wingerter A, Neu MA, El Malki K, Alt F, Roth L, Marini
F, Ottenhausen M, Glaser M, Knuf M, Russo A, Faber J.
Identification of an Immunogenic Medulloblastoma-Specific Fusion
Involving EPC2 and GULP1. Cancers. 2021;13(22):5838. doi:10.3390/cancers13225838
- Krämer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga-García
R, Schulte-Schrepping J, Kaiser KM, Rieke GJ, Bischoff J, Monin MB,
Hoffmeister C, Schlabe S, De Domenico E, Reusch N, Händler K, Reynolds
G, Blüthgen N, Hack G, Finnemann C, Nischalke HD, Strassburg CP,
Stephenson E, Su Y, Gardner L, Yuan D, Chen D, Goldman J, Rosenstiel P,
Schmidt SV, Latz E, Hrusovsky K, Ball AJ, Johnson JM, Koenig PA, Schmidt
FI, Haniffa M, Heath JR, Kümmerer BM, Keitel V, Jensen B, Stubbemann P,
Kurth F, Sander LE, Sawitzki B, Aschenbrenner AC, Schultze JL,
Nattermann J, Altmüller J, Angelov A, Aschenbrenner AC, Bals R,
Bartholomäus A, Becker A, Becker M, Bezdan D, Bitzer M, Blumert C,
Bonifacio E, Bork P, Boyke B, Blum H, Casadei N, Clavel T, Colome-Tatche
M, Cornberg M, De La Rosa Velázquez IA, Diefenbach A, Dilthey A, Fischer
N, Förstner K, Franzenburg S, Frick JS, Gabernet G, Gagneur J,
Ganzenmueller T, Gauder M, Geißert J, Goesmann A, Göpel S, Grundhoff A,
Grundmann H, Hain T, Hanses F, Hehr U, Heimbach A, Hoeper M, Horn F,
Hübschmann D, Hummel M, Iftner T, Iftner A, Illig T, Janssen S,
Kalinowski J, Kallies R, Kehr B, Keller A, et al. Early IFN-α signatures
and persistent dysfunction are distinguishing features of NK cells in
severe COVID-19. Immunity. 2021;54(11):2650-2669.e14. doi:10.1016/j.immuni.2021.09.002
- Reich TR, Schwarzenbach C, Vilar JB, Unger S, Mühlhäusler F,
Nikolova T, Poplawski A, Baymaz HI, Beli P, Christmann
M, Tomicic MT. Localization matters: nuclear-trapped Survivin sensitizes
glioblastoma cells to temozolomide by elevating cellular senescence and
impairing homologous recombination. Cellular and Molecular Life
Sciences. 2021;78(14):5587-5604. doi:10.1007/s00018-021-03864-0
- Czauderna C, Poplawski A, O’Rourke CJ, Castven D,
Pérez-Aguilar B, Becker D, Heilmann-Heimbach S, Odenthal M, Amer W,
Schmiel M, Drebber U, Binder H, Ridder DA,
Schindeldecker M, Straub BK, Galle PR, Andersen JB, Thorgeirsson SS,
Park YN, Marquardt JU. Epigenetic modifications precede
molecular alterations and drive human hepatocarcinogenesis. JCI Insight.
2021;6(17). doi:10.1172/jci.insight.146196
- Notarbartolo S, Ranzani V, Bandera A, Gruarin P, Bevilacqua V,
Putignano AR, Gobbini A, Galeota E, Manara C, Bombaci M, Pesce E, Zagato
E, Favalli A, Sarnicola ML, Curti S, Crosti M, Martinovic M, Fabbris T,
Marini F, Donnici L, Lorenzo M, Mancino M, Ungaro R,
Lombardi A, Mangioni D, Muscatello A, Aliberti S, Blasi F, De Feo T,
Prati D, Manganaro L, Granucci F, Lanzavecchia A, Francesco RD, Gori A,
Grifantini R, Abrignani S. Integrated longitudinal immunophenotypic,
transcriptional, and repertoire analyses delineate immune responses in
patients with COVID-19. Science Immunology. 2021;6(62). doi:10.1126/sciimmunol.abg5021
- Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han
X, Ong JS, Hewitt AW, Segrè AV, Rouhana JM, Hamel AR, Igo RP, Choquet H,
Qassim A, Josyula NS, Cooke Bailey JN, Bonnemaijer PWM, Iglesias A,
Siggs OM, Young TL, Vitart V, Thiadens AAHJ, Karjalainen J, Uebe S,
Melles RB, Nair KS, Luben R, Simcoe M, Amersinghe N, Cree AJ, Hohn R,
Poplawski A, Chen LJ, Rong SS, Aung T, Vithana EN,
Tamiya G, Shiga Y, Yamamoto M, Nakazawa T, Currant H, Birney E, Wang X,
Auton A, Lupton MK, Martin NG, Ashaye A, Olawoye O, Williams SE, Akafo
S, Ramsay M, Hashimoto K, Kamatani Y, Akiyama M, Momozawa Y, Foster PJ,
Khaw PT, Morgan JE, Strouthidis NG, Kraft P, Kang JH, Pang CP, Pasutto
F, Mitchell P, Lotery AJ, Palotie A, van Duijn C, Haines JL, Hammond C,
Pasquale LR, Klaver CCW, Hauser M, Khor CC, Mackey DA, Kubo M, Cheng CY,
Craig JE, MacGregor S, Wiggs JL. Genome-wide meta-analysis identifies
127 open-angle glaucoma loci with consistent effect across ancestries.
Nature Communications. 2021;12(1). doi:10.1038/s41467-020-20851-4
- Marini F, Scherzinger D, Danckwardt S. TREND-DB—a
transcriptome-wide atlas of the dynamic landscape of alternative
polyadenylation. Nucleic Acids Research. 2020;49(D1):D243-D253. doi:10.1093/nar/gkaa722
- Gaonkar KS, Marini F, Rathi KS, Jain P, Zhu Y,
Chimicles NA, Brown MA, Naqvi AS, Zhang B, Storm PB, Maris JM, Raman P,
Resnick AC, Strauch K, Taroni JN, Rokita JL. annoFuse:
an R Package to annotate, prioritize, and interactively explore putative
oncogenic RNA fusions. BMC Bioinformatics. 2020;21(1). doi:10.1186/s12859-020-03922-7
- Bogucka K, Marini F, Rosigkeit S, Schloeder J,
Jonuleit H, David K, Schlackow M, Rajalingam K. ERK3/MAPK6 is required
for KRAS-mediated NSCLC tumorigenesis. Cancer Gene Therapy.
2020;28(5):359-374. doi:10.1038/s41417-020-00245-w
- Marini F, Linke J, Binder H.
ideal: an R/Bioconductor package for interactive differential expression
analysis. BMC Bioinformatics. 2020;21(1). doi:10.1186/s12859-020-03819-5
- Brackmann LK, Poplawski A, Grandt CL, Schwarz H,
Hankeln T, Rapp S, Zahnreich S, Galetzka D, Schmitt I, Grad C, Eckhard
L, Mirsch J, Blettner M, Scholz-Kreisel P, Hess M,
Binder H, Schmidberger H, Marron M. Comparison of time
and dose dependent gene expression and affected pathways in primary
human fibroblasts after exposure to ionizing radiation. Molecular
Medicine. 2020;26(1). doi:10.1186/s10020-020-00203-0
- Roewe J, Stavrides G, Strueve M, Sharma A, Marini
F, Mann A, Smith SA, Kaya Z, Strobl B, Mueller M, Reinhardt C,
Morrissey JH, Bosmann M. Bacterial polyphosphates interfere with the
innate host defense to infection. Nature Communications. 2020;11(1). doi:10.1038/s41467-020-17639-x
- Hauptmann J, Johann L, Marini F, Kitic M, Colombo
E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC,
Klein M, Cardoso S, Strauß J, Bolisetty S, Lühder F, Schwaninger M,
Binder H, Bechman I, Bopp T, Agarwal A, Soares MP,
Regen T, Waisman A. Interleukin-1 promotes autoimmune neuroinflammation
by suppressing endothelial heme oxygenase-1 at the blood–brain barrier.
Acta Neuropathologica. 2020;140(4):549-567. doi:10.1007/s00401-020-02187-x
- Soneson C, Marini F, Geier F, Love MI, Stadler MB.
ExploreModelMatrix: Interactive exploration for improved understanding
of design matrices and linear models in R. F1000Research. 2020;9:512. doi:10.12688/f1000research.24187.1
- Bogucka K, Pompaiah M, Marini F, Binder
H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit
S, Grimminger P, Schild H, Rajalingam K. ERK3/MAPK6 controls IL-8
production and chemotaxis. eLife. 2020;9. doi:10.7554/elife.52511
- Mohebiany AN, Ramphal NS, Karram K, Di Liberto G, Novkovic T, Klein
M, Marini F, Kreutzfeldt M, Härtner F, Lacher SM, Bopp
T, Mittmann T, Merkler D, Waisman A. Microglial A20 Protects the Brain
from CD8 T-Cell-Mediated Immunopathology. Cell Reports.
2020;30(5):1585-1597.e6. doi:10.1016/j.celrep.2019.12.097
- Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang
Y, Klein M, Bittner S, Steffen F, Moos S, Marini F,
Gloury R, Kurschus FC, Chao YY, Bertrams W, Sexl V, Schmeck B, Bonetti
L, Grusdat M, Lohoff M, Zielinski CE, Zipp F, Kallies A, Brenner D,
Berger M, Bopp T, Tackenberg B, Huber M. IL-17+ CD8+ T cell suppression
by dimethyl fumarate associates with clinical response in multiple
sclerosis. Nature Communications. 2019;10(1). doi:10.1038/s41467-019-13731-z
- Amezquita RA, Lun ATL, Becht E, Carey VJ, Carpp LN, Geistlinger L,
Marini F, Rue-Albrecht K, Risso D, Soneson C, Waldron
L, Pagès H, Smith ML, Huber W, Morgan M, Gottardo R, Hicks SC.
Orchestrating single-cell analysis with Bioconductor. Nature Methods.
2019;17(2):137-145. doi:10.1038/s41592-019-0654-x
- Marini F, Binder H. pcaExplorer:
an R/Bioconductor package for interacting with RNA-seq principal
components. BMC Bioinformatics. 2019;20(1). doi:10.1186/s12859-019-2879-1
- Graf C, Wilgenbus P, Pagel S, Pott J, Marini F,
Reyda S, Kitano M, Macher-Göppinger S, Weiler H, Ruf W. Myeloid
cell–synthesized coagulation factor X dampens antitumor immunity.
Science Immunology. 2019;4(39). doi:10.1126/sciimmunol.aaw8405
- Akhtar J, More P, Albrecht S, Marini F, Kaiser W,
Kulkarni A, Wojnowski L, Fontaine JF, Andrade-Navarro MA, Silies M,
Berger C. TAF-ChIP: an ultra-low input approach for genome-wide
chromatin immunoprecipitation assay. Life Science Alliance.
2019;2(4):e201900318. doi:10.26508/lsa.201900318
- Akhtar J, Kreim N, Marini F, Mohana G, Brüne D,
Binder H, Roignant JY. Promoter-proximal pausing
mediated by the exon junction complex regulates splicing. Nature
Communications. 2019;10(1). doi:10.1038/s41467-019-08381-0
- Ogorodnikov A, Levin M, Tattikota S, Tokalov S, Hoque M, Scherzinger
D, Marini F, Poetsch A, Binder H,
Macher-Göppinger S, Probst HC, Tian B, Schaefer M, Lackner KJ,
Westermann F, Danckwardt S. Transcriptome 3′end organization by PCF11
links alternative polyadenylation to formation and neuronal
differentiation of neuroblastoma. Nature Communications. 2018;9(1). doi:10.1038/s41467-018-07580-5
- Nührenberg TG, Cederqvist M, Marini F, Stratz C,
Grüning BA, Trenk D, Binder H, Gilsbach R, Neumann FJ,
Hein L. Uncontrolled Diabetes Mellitus Has No Major Influence on the
Platelet Transcriptome. BioMed Research International. 2018;2018:1-9. doi:10.1155/2018/8989252
- Haase T, Müller C, Krause J, Röthemeier C, Stenzig J, Kunze S,
Waldenberger M, Münzel T, Pfeiffer N, Wild P, Michal M, Marini
F, Karakas M, Lackner K, Blankenberg S, Zeller T. Novel DNA
Methylation Sites Influence GPR15 Expression in Relation to Smoking.
Biomolecules. 2018;8(3):74. doi:10.3390/biom8030074
- Rue-Albrecht K, Marini F, Soneson C, Lun ATL. iSEE:
Interactive SummarizedExperiment Explorer. F1000Research. 2018;7:741. doi:10.12688/f1000research.14966.1
- Goesswein D, Habtemichael N, Gerhold-Ay A,
Mazur J, Wünsch D, Knauer SK, Künzel J, Matthias C,
Strieth S, Stauber RH. Expressional analysis of disease-relevant
signalling-pathways in primary tumours and metastasis of head and neck
cancers. Scientific Reports. 2018;8(1). doi:10.1038/s41598-018-25512-7
- Foerster F, Hess M,
Gerhold-Ay A, Marquardt JU, Becker D,
Galle PR, Schuppan D, Binder H, Bockamp E. The immune
contexture of hepatocellular carcinoma predicts clinical outcome.
Scientific Reports. 2018;8(1). doi:10.1038/s41598-018-21937-2
- Shen L, Tenzer S, Hess M, Distler U, Tubbe I,
Montermann E, Schimmer S, Dittmer U, Grabbe S, Bros M. Friend virus
limits adaptive cellular immune responses by imprinting a
maturation-resistant and T helper type 2-biased immunophenotype in
dendritic cells. Santiago ML, ed. PLOS ONE. 2018;13(2):e0192541. doi:10.1371/journal.pone.0192541
- Hess M, Lenz S, Blätte TJ, Bullinger L,
Binder H. Partitioned learning of deep Boltzmann
machines for SNP data. Hancock J, ed. Bioinformatics.
2017;33(20):3173-3180. doi:10.1093/bioinformatics/btx408
- Yurugi H, Marini F, Weber C, David K, Zhao Q,
Binder H, Désaubry L, Rajalingam K. Targeting
prohibitins with chemical ligands inhibits KRAS-mediated lung tumours.
Oncogene. 2017;36(33):4778-4789. doi:10.1038/onc.2017.93
- Campos Carrascosa L, Klein M, Kitagawa Y, Lückel C, Marini
F, König A, Guralnik A, Raifer H, Hagner-Benes S, Rädler D,
Böck A, Kang C, Lohoff M, Garn H, Schaub B, Berberich-Siebelt F,
Sakaguchi S, Bopp T, Huber M. Reciprocal regulation of the Il9 locus by
counteracting activities of transcription factors IRF1 and IRF4. Nature
Communications. 2017;8(1). doi:10.1038/ncomms15366
- Iglesias AI, der Lee SJ, Bonnemaijer PWM, Höhn R, Nag A, Gharahkhani
P, Khawaja AP, Broer L, Foster PJ, Hammond CJ, Hysi PG, Leeuwen EM,
MacGregor S, Mackey DA, Mazur J, Nickels S,
Uitterlinden AG, Klaver CCW, Amin N, Duijn CM. Haplotype reference
consortium panel: Practical implications of imputations with large
reference panels. Human Mutation. 2017;38(8):1025-1032. doi:10.1002/humu.23247
- Hafner C, Wu J, Tiboldi A, Hess M, Mitulovic G,
Kaun C, Krychtiuk KA, Wojta J, Ullrich R, Tretter EV, Markstaller K,
Klein KU. Hyperoxia Induces Inflammation and Cytotoxicity in Human Adult
Cardiac Myocytes. Shock. 2017;47(4):436-444. doi:10.1097/shk.0000000000000740
- Sennblad B, Basu S, Mazur J, Suchon P,
Martinez-Perez A, van Hylckama Vlieg A, Truong V, Li Y, Gådin JR, Tang
W, Grossman V, de Haan HG, Handin N, Silveira A, Souto JC,
Franco-Cereceda A, Morange PE, Gagnon F, Soria JM, Eriksson P, Hamsten
A, Maegdefessel L, Rosendaal FR, Wild P, Folsom AR, Trégouët DA,
Sabater-Lleal M. Genome-wide association study with additional genetic
and post-transcriptional analyses reveals novel regulators of plasma
factor XI levels. Human Molecular Genetics. Published online January 4,
2017:ddw401. doi:10.1093/hmg/ddw401
- de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS,
Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M,
Weng LC, Pool R, Grossmann V, Brody JA, Venturini C, Tanaka T, Rose LM,
Oldmeadow C, Mazur J, Basu S, Frånberg M, Yang Q,
Ligthart S, Hottenga JJ, Rumley A, Mulas A, de Craen AJM, Grotevendt A,
Taylor KD, Delgado GE, Kifley A, Lopez LM, Berentzen TL, Mangino M,
Bandinelli S, Morrison AC, Hamsten A, Tofler G, de Maat MPM, Draisma
HHM, Lowe GD, Zoledziewska M, Sattar N, Lackner KJ, Völker U, McKnight
B, Huang J, Holliday EG, McEvoy MA, Starr JM, Hysi PG, Hernandez DG,
Guan W, Rivadeneira F, McArdle WL, Slagboom PE, Zeller T, Psaty BM,
Uitterlinden AG, de Geus EJC, Stott DJ, Binder H,
Hofman A, Franco OH, Rotter JI, Ferrucci L, Spector TD, Deary IJ, März
W, Greinacher A, Wild PS, Cucca F, Boomsma DI, Watkins H, Tang W, Ridker
PM, Jukema JW, Scott RJ, Mitchell P, Hansen T, O’Donnell CJ, Smith NL,
Strachan DP, Dehghan A. Comparison of HapMap and 1000 Genomes Reference
Panels in a Large-Scale Genome-Wide Association Study. Yao YG, ed. PLOS
ONE. 2017;12(1):e0167742. doi:10.1371/journal.pone.0167742
- Poplawski A, Binder H. Feasibility
of sample size calculation for RNA-seq studies. Briefings in
Bioinformatics. Published online January 18, 2017:bbw144. doi:10.1093/bib/bbw144
- Hahn M, Bürckert JP, Luttenberger CA, Klebow S, Hess
M, Al-Maarri M, Vogt M, Reißig S, Hallek M,
Wienecke-Baldacchino A, Buch T, Muller CP, Pallasch CP, Wunderlich FT,
Waisman A, Hövelmeyer N. Aberrant splicing of the tumor suppressor CYLD
promotes the development of chronic lymphocytic leukemia via sustained
NF-κB signaling. Leukemia. 2017;32(1):72-82. doi:10.1038/leu.2017.168
- Wasser B, Pramanik G, Hess M, Klein M, Luessi F,
Dornmair K, Bopp T, Zipp F, Witsch E. Increase of Alternatively
Activated Antigen Presenting Cells in Active Experimental Autoimmune
Encephalomyelitis. Journal of Neuroimmune Pharmacology.
2016;11(4):721-732. doi:10.1007/s11481-016-9696-3
- Paret C, Theruvath J, Russo A, Kron B, Malki KE, Lehmann N,
Wingerter A, Neu MA, Gerhold-Ay A, Wagner W, Sommer C,
Pietsch T, Seidmann L, Faber J. Activation of the basal cell carcinoma
pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for
personalized targeted therapy. Oncotarget. 2016;7(50):83378-83391. doi:10.18632/oncotarget.13092
- Tideman JWL, Fan Q, Polling JR, Guo X, Yazar S, Khawaja A, Höhn R,
Lu Y, Jaddoe VWV, Yamashiro K, Yoshikawa M, Gerhold-Ay
A, Nickels S, Zeller T, He M, Boutin T, Bencic G, Vitart V,
Mackey DA, Foster PJ, MacGregor S, Williams C, Saw SM, Guggenheim JA,
Klaver CCW. When do myopia genes have their effect? Comparison of
genetic risks between children and adults. Genetic Epidemiology.
2016;40(8):756-766. doi:10.1002/gepi.21999
- Gehrke N, Wörns MA, Huber Y, Hess M, Straub BK,
Hövelmeyer N, Waisman A, Kim YO, Schuppan D, Galle PR, Schattenberg JM.
Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation
through insulin-sensitive metabolic transcription factors. Journal of
Hepatology. 2016;65(6):1188-1197. doi:10.1016/j.jhep.2016.06.026
- Fan Q, Verhoeven VJM, Wojciechowski R, Barathi VA, Hysi PG,
Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM,
Lehtimäki T, Lu Y, Haller T, Xie J, Delcourt C, Pirastu M, Wedenoja J,
Gharahkhani P, Venturini C, Miyake M, Hewitt AW, Guo X, Mazur
J, Huffman JE, Williams KM, Polasek O, Campbell H, Rudan I,
Vatavuk Z, Wilson JF, Joshi PK, McMahon G, St Pourcain B, Evans DM,
Simpson CL, Schwantes-An TH, Igo RP, Mirshahi A, Cougnard-Gregoire A,
Bellenguez C, Blettner M, Raitakari O, Kähönen M, Seppälä I, Zeller T,
Meitinger T, Ried JS, Gieger C, Portas L, van Leeuwen EM, Amin N,
Uitterlinden AG, Rivadeneira F, Hofman A, Vingerling JR, Wang YX, Wang
X, Tai-Hui Boh E, Ikram MK, Sabanayagam C, Gupta P, Tan V, Zhou L, Ho
CEH, Lim W, Beuerman RW, Siantar R, Tai ES, Vithana E, Mihailov E, Khor
CC, Hayward C, Luben RN, Foster PJ, Klein BEK, Klein R, Wong HS,
Mitchell P, Metspalu A, Aung T, Young TL, He M, Pärssinen O, van Duijn
CM, Jin Wang J, Williams C, Jonas JB, Teo YY, Mackey DA, Oexle K,
Yoshimura N, Paterson AD, Pfeiffer N, Wong TY, Baird PN, Stambolian D,
et al. Meta-analysis of gene–environment-wide association scans
accounting for education level identifies additional loci for refractive
error. Nature Communications. 2016;7(1). doi:10.1038/ncomms11008
- Tuettenberg A, Hahn SA, Mazur J, Gerhold-Ay
A, Scholma J, Marg I, Ulges A, Satoh K, Bopp T, Joore J,
Jonuleit H. Kinome Profiling of Regulatory T Cells: A Closer Look into a
Complex Intracellular Network. Unutmaz D, ed. PLOS ONE.
2016;11(2):e0149193. doi:10.1371/journal.pone.0149193
- de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri
M, Tang W, Teumer A, Marioni RE, Grossmann V, Hottenga JJ, Trompet S,
Müller-Nurasyid M, Zhao JH, Brody JA, Kleber ME, Guo X, Wang JJ, Auer
PL, Attia JR, Yanek LR, Ahluwalia TS, Lahti J, Venturini C, Tanaka T,
Bielak LF, Joshi PK, Rocanin-Arjo A, Kolcic I, Navarro P, Rose LM,
Oldmeadow C, Riess H, Mazur J, Basu S, Goel A, Yang Q,
Ghanbari M, Willemsen G, Rumley A, Fiorillo E, de Craen AJM, Grotevendt
A, Scott R, Taylor KD, Delgado GE, Yao J, Kifley A, Kooperberg C, Qayyum
R, Lopez LM, Berentzen TL, Räikkönen K, Mangino M, Bandinelli S, Peyser
PA, Wild S, Trégouët DA, Wright AF, Marten J, Zemunik T, Morrison AC,
Sennblad B, Tofler G, de Maat MPM, de Geus EJC, Lowe GD, Zoledziewska M,
Sattar N, Binder H, Völker U, Waldenberger M, Khaw KT,
Mcknight B, Huang J, Jenny NS, Holliday EG, Qi L, Mcevoy MG, Becker DM,
Starr JM, Sarin AP, Hysi PG, Hernandez DG, Jhun MA, Campbell H, Hamsten
A, Rivadeneira F, Mcardle WL, Slagboom PE, Zeller T, Koenig W, Psaty BM,
Haritunians T, Liu J, Palotie A, Uitterlinden AG, Stott DJ, et al. A
meta-analysis of 120 246 individuals identifies 18 new loci for
fibrinogen concentration. Human Molecular Genetics. 2015;25(2):358-370.
doi:10.1093/hmg/ddv454
- Poplawski A, Marini F,
Hess M, Zeller T, Mazur J,
Binder H. Systematically evaluating interfaces for
RNA-seq analysis from a life scientist perspective. Briefings in
Bioinformatics. 2015;17(2):213-223. doi:10.1093/bib/bbv036
- Feldmeyer B, Mazur J, Beros S, Lerp H,
Binder H, Foitzik S. Gene expression patterns
underlying parasite-induced alterations in host behaviour and life
history. Molecular Ecology. 2016;25(2):648-660. doi:10.1111/mec.13498
- Bruttger J, Karram K, Wörtge S, Regen T, Marini F,
Hoppmann N, Klein M, Blank T, Yona S, Wolf Y, Mack M, Pinteaux E, Müller
W, Zipp F, Binder H, Bopp T, Prinz M, Jung S, Waisman
A. Genetic Cell Ablation Reveals Clusters of Local Self-Renewing
Microglia in the Mammalian Central Nervous System. Immunity.
2015;43(1):92-106. doi:10.1016/j.immuni.2015.06.012
- Hermanns MI, Grossmann V, Spronk HMH, Schulz A, Jünger C,
Laubert-Reh D, Mazur J, Gori T, Zeller T, Pfeiffer N,
Beutel M, Blankenberg S, Münzel T, Lackner KJ, ten Cate-Hoek AJ, ten
Cate H, Wild PS. Distribution, genetic and cardiovascular determinants
of FVIII:c — Data from the population-based Gutenberg Health Study.
International Journal of Cardiology. 2015;187:166-174. doi:10.1016/j.ijcard.2015.03.330
- Schwarz A, Tenzer S, Hackenberg M, Erhart J, Gerhold-Ay
A, Mazur J, Kuharev J, Ribeiro JMC, Kotsyfakis
M. A Systems Level Analysis Reveals Transcriptomic and Proteomic
Complexity in Ixodes Ricinus Midgut and Salivary Glands During Early
Attachment and Feeding. Molecular & Cellular Proteomics.
2014;13(10):2725-2735. doi:10.1074/mcp.m114.039289
- Binder H, Gefeller O, Schmid M, Mayr A. The
Evolution of Boosting Algorithms. Methods of Information in Medicine.
2014;53(06):419-427. doi:10.3414/me13-01-0122
- Becker D, Sfakianakis I, Krupp M, Staib F, Gerhold-Ay
A, Victor A, Binder H, Blettner M, Maass T,
Thorgeirsson S, Galle PR, Teufel A. Genetic signatures shared in
embryonic liver development and liver cancer define prognostically
relevant subgroups in HCC. Molecular Cancer. 2012;11(1). doi:10.1186/1476-4598-11-55
- Paret C, Russo A, Lehmann N, Backes N, Roth L, Malki KE, Wingerter
A, Neu MA, Seidmann L, Gerhold-Ay A, Wagner W, Faber J.
TRTH-08. HIGH GRADE NEUROEPITHELIAL TUMOR OF THE CENTRAL NERVOUS SYSTEM
WITH BCOR ALTERATION IS SENSITIVE TO IGF1R INHIBITION. Neuro-Oncology.
2017;19(suppl_4):iv53-iv53. doi:10.1093/neuonc/nox083.220
- Paret C, Theruvath J, Russo A, Kron B, ElMalki K, Lehmann N, Neu M,
Gerhold-Ay A, Wagner W, Sommer C, Seidmann L, Faber J.
PNR-35CNS HGNET-BCOR - MOLECULAR CHARACTERIZATION AND IDENTIFICATION OF
POSSIBLE THERAPEUTIC TARGETS OF A NEW BRAIN TUMOR ENTITY.
Neuro-Oncology. 2016;18(suppl 3):iii14.1-iii14. doi:10.1093/neuonc/now067.30
- Marini F, Binder H. Development of
Applications for Interactive and Reproducible Research: a Case Study.
Genomics and Computational Biology. 2016;3(1):39. doi:10.18547/gcb.2017.vol3.iss1.e39
Um eine vollständige Liste der Veröffentlichungen einzusehen, besuchen Sie bitte Pubmed und geben Sie die entsprechenden Initialen ein (e.g. "Marini F", "Foerster F", "Poplawski A", "Ludt A", ...).
Einige Manuskripte sind auch zu finden auf https://www.biorxiv.org