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Publikationen

Hier finden Sie eine Liste der Publikationen, bei denen Mitglieder des BIUM-MZ einen Beitrag leisteten:


  1. Bartneck J, Hartmann AK, Stein L, Arnold-Schild D, Klein M, Stassen M, Marini F, Pielenhofer J, Meiser SL, Langguth P, Mack M, Muth S, Probst HC, Schild H, Radsak MP. Tumor-infiltrating CCR2+ inflammatory monocytes counteract specific immunotherapy. Frontiers in Immunology. 2023;14. doi:10.3389/fimmu.2023.1267866
  2. Rosellini M, Schulze A, Omer EA, Ali NT, Marini F, Küpper JH, Efferth T. The Effect of Plastic-Related Compounds on Transcriptome-Wide Gene Expression on CYP2C19-Overexpressing HepG2 Cells. Molecules. 2023;28(16):5952. doi:10.3390/molecules28165952
  3. ten Cate V, Rapp S, Schulz A, Pallares Robles A, Jurk K, Koeck T, Espinola-Klein C, Halank M, Seyfarth HJ, Beutel ME, Schuster AK, Marini F, Hobohm L, Lankeit M, Lackner KJ, Ruf W, Münzel T, Andrade-Navarro MA, Prochaska JH, Konstantinides SV, Wild PS. Circulating microRNAs predict recurrence and death following venous thromboembolism. Journal of Thrombosis and Haemostasis. 2023;21(10):2797-2810. doi:10.1016/j.jtha.2023.07.010
  4. Pontarollo G, Kollar B, Mann A, Khuu MP, Kiouptsi K, Bayer F, Brandão I, Zinina VV, Hahlbrock J, Malinarich F, Mimmler M, Bhushan S, Marini F, Ruf W, Belheouane M, Baines JF, Endres K, Reba SM, Raker VK, Deppermann C, Welsch C, Bosmann M, Soshnikova N, Chassaing B, Bergentall M, Sommer F, Bäckhed F, Reinhardt C. Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling. Nature Metabolism. 2023;5(7):1174-1187. doi:10.1038/s42255-023-00828-5
  5. Grandt CL, Brackmann LK, Poplawski A, Schwarz H, Marini F, Hankeln T, Galetzka D, Zahnreich S, Mirsch J, Spix C, Blettner M, Schmidberger H, Marron M. Identification of lncRNAs involved in response to ionizing radiation in fibroblasts of long-term survivors of childhood cancer and cancer-free controls. Frontiers in Oncology. 2023;13. doi:10.3389/fonc.2023.1158176
  6. Grandt CL, Brackmann LK, Foraita R, Schwarz H, Hummel-Bartenschlager W, Hankeln T, Kraemer C, Zahnreich S, Drees P, Mirsch J, Spix C, Blettner M, Schmidberger H, Binder H, Hess M, Galetzka D, Marini F, Poplawski A, Marron M. Gene expression variability in long-term survivors of childhood cancer and cancer-free controls in response to ionizing irradiation. Molecular Medicine. 2023;29(1). doi:10.1186/s10020-023-00629-2
  7. Ha CSR, Müller-Nurasyid M, Petrera A, Hauck SM, Marini F, Bartsch DK, Slater EP, Strauch K. Proteomics biomarker discovery for individualized prevention of familial pancreatic cancer using statistical learning. Batra SK, ed. PLOS ONE. 2023;18(1):e0280399. doi:10.1371/journal.pone.0280399
  8. Britto-Borges T, Ludt A, Boileau E, Gjerga E, Marini F, Dieterich C. Magnetique: an interactive web application to explore transcriptome signatures of heart failure. Journal of Translational Medicine. 2022;20(1). doi:10.1186/s12967-022-03694-z
  9. Sohl J, Hartmann AK, Hahlbrock J, Bartneck J, Stassen M, Klein M, Bros M, Grabbe S, Marini F, Woods K, Guezguez B, Mack M, Schild H, Muth S, Melchior F, Probst HC, Langguth P, Radsak MP. Dithranol as novel co-adjuvant for non-invasive dermal vaccination. npj Vaccines. 2022;7(1). doi:10.1038/s41541-022-00530-9
  10. Dietrich A, Sturm G, Merotto L, Marini F, Finotello F, List M. SimBu: bias-aware simulation of bulk RNA-seq data with variable cell-type composition. Bioinformatics. 2022;38(Supplement_2):ii141-ii147. doi:10.1093/bioinformatics/btac499
  11. Grandt CL, Brackmann LK, Poplawski A, Schwarz H, Hummel-Bartenschlager W, Hankeln T, Kraemer C, Marini F, Zahnreich S, Schmitt I, Drees P, Mirsch J, Grabow D, Schmidberger H, Binder H, Hess M, Galetzka D, Marron M. Radiation-response in primary fibroblasts of long-term survivors of childhood cancer with and without second primary neoplasms: the KiKme study. Molecular Medicine. 2022;28(1). doi:10.1186/s10020-022-00520-6
  12. Bensaoud C, Tenzer S, Poplawski A, Medina JM, Jmel MA, Voet H, Mekki I, Aparicio‐Puerta E, Cuveele B, Distler U, Marini F, Hackenberg M, Kotsyfakis M. Quantitative proteomics analysis reveals core and variable tick salivary proteins at the tick‐vertebrate host interface. Molecular Ecology. 2022;31(15):4162-4175. doi:10.1111/mec.16561
  13. Ludt A, Ustjanzew A, Binder H, Strauch K, Marini F. Interactive and Reproducible Workflows for Exploring and Modeling RNA‐seq Data with pcaExplorer, Ideal, and GeneTonic. Current Protocols. 2022;2(4). doi:10.1002/cpz1.411
  14. Das Gupta D, Paul C, Samel N, Bieringer M, Staudenraus D, Marini F, Raifer H, Menke L, Hansal L, Camara B, Roth E, Daum P, Wanzel M, Mernberger M, Nist A, Bauer UM, Helmprobst F, Buchholz M, Roth K, Bastian L, Hartmann AM, Baldus C, Ikuta K, Neubauer A, Burchert A, Jäck HM, Klein M, Bopp T, Stiewe T, Pagenstecher A, Lohoff M. IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity. Cell Death & Differentiation. 2022;29(11):2163-2176. doi:10.1038/s41418-022-01005-z
  15. Mooz J, Riegel K, PS H, Sadanandam A, Marini F, Klein M, Werner U, Roth W, Wilken-Schmitz A, Tegeder I, Rajalingam K. ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers. Science Advances. 2022;8(11). doi:10.1126/sciadv.abk1538
  16. Kaps L, Huppertsberg A, Choteschovsky N, Klefenz A, Durak F, Schrörs B, Diken M, Eichler E, Rosigkeit S, Schmitt S, Leps C, Schulze A, Foerster F, Bockamp E, De Geest BG, Koynov K, Räder HJ, Tenzer S, Marini F, Schuppan D, Nuhn L. pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages. Proceedings of the National Academy of Sciences. 2022;119(12). doi:10.1073/pnas.2122310119
  17. Nührenberg TG, Stöckle J, Marini F, Zurek M, Grüning BA, Benes V, Hein L, Neumann FJ, Stratz C, Cederqvist M, Hochholzer W. Impact of high platelet turnover on the platelet transcriptome: Results from platelet RNA-sequencing in patients with sepsis. James K, ed. PLOS ONE. 2022;17(1):e0260222. doi:10.1371/journal.pone.0260222
  18. Ridder DA, Urbansky LL, Witzel HR, Schindeldecker M, Weinmann A, Berndt K, Gerber TS, Köhler BC, Nichetti F, Ludt A, Gehrke N, Schattenberg JM, Heinrich S, Roth W, Straub BK. Transforming Growth Factor-β Activated Kinase 1 (Tak1) Is Activated in Hepatocellular Carcinoma, Mediates Tumor Progression, and Predicts Unfavorable Outcome. Cancers. 2022;14(2):430. doi:10.3390/cancers14020430
  19. Marini F, Ludt A, Linke J, Strauch K. GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data. BMC Bioinformatics. 2021;22(1). doi:10.1186/s12859-021-04461-5
  20. Ustjanzew A, Desuki A, Ritzel C, Dolezilek AC, Wagner DC, Christoph J, Unberath P, Kindler T, Faber J, Marini F, Panholzer T, Paret C. cbpManager: a web application to streamline the integration of clinical and genomic data in cBioPortal to support the Molecular Tumor Board. BMC Medical Informatics and Decision Making. 2021;21(1). doi:10.1186/s12911-021-01719-z
  21. Paret C, Lehmann N, Bender H, Sprang M, Sommer CJ, Cana D, Seidmann L, Wingerter A, Neu MA, El Malki K, Alt F, Roth L, Marini F, Ottenhausen M, Glaser M, Knuf M, Russo A, Faber J. Identification of an Immunogenic Medulloblastoma-Specific Fusion Involving EPC2 and GULP1. Cancers. 2021;13(22):5838. doi:10.3390/cancers13225838
  22. Krämer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga-García R, Schulte-Schrepping J, Kaiser KM, Rieke GJ, Bischoff J, Monin MB, Hoffmeister C, Schlabe S, De Domenico E, Reusch N, Händler K, Reynolds G, Blüthgen N, Hack G, Finnemann C, Nischalke HD, Strassburg CP, Stephenson E, Su Y, Gardner L, Yuan D, Chen D, Goldman J, Rosenstiel P, Schmidt SV, Latz E, Hrusovsky K, Ball AJ, Johnson JM, Koenig PA, Schmidt FI, Haniffa M, Heath JR, Kümmerer BM, Keitel V, Jensen B, Stubbemann P, Kurth F, Sander LE, Sawitzki B, Aschenbrenner AC, Schultze JL, Nattermann J, Altmüller J, Angelov A, Aschenbrenner AC, Bals R, Bartholomäus A, Becker A, Becker M, Bezdan D, Bitzer M, Blumert C, Bonifacio E, Bork P, Boyke B, Blum H, Casadei N, Clavel T, Colome-Tatche M, Cornberg M, De La Rosa Velázquez IA, Diefenbach A, Dilthey A, Fischer N, Förstner K, Franzenburg S, Frick JS, Gabernet G, Gagneur J, Ganzenmueller T, Gauder M, Geißert J, Goesmann A, Göpel S, Grundhoff A, Grundmann H, Hain T, Hanses F, Hehr U, Heimbach A, Hoeper M, Horn F, Hübschmann D, Hummel M, Iftner T, Iftner A, Illig T, Janssen S, Kalinowski J, Kallies R, Kehr B, Keller A, et al. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. 2021;54(11):2650-2669.e14. doi:10.1016/j.immuni.2021.09.002
  23. Notarbartolo S, Ranzani V, Bandera A, Gruarin P, Bevilacqua V, Putignano AR, Gobbini A, Galeota E, Manara C, Bombaci M, Pesce E, Zagato E, Favalli A, Sarnicola ML, Curti S, Crosti M, Martinovic M, Fabbris T, Marini F, Donnici L, Lorenzo M, Mancino M, Ungaro R, Lombardi A, Mangioni D, Muscatello A, Aliberti S, Blasi F, De Feo T, Prati D, Manganaro L, Granucci F, Lanzavecchia A, Francesco RD, Gori A, Grifantini R, Abrignani S. Integrated longitudinal immunophenotypic, transcriptional, and repertoire analyses delineate immune responses in patients with COVID-19. Science Immunology. 2021;6(62). doi:10.1126/sciimmunol.abg5021
  24. Czauderna C, Poplawski A, O’Rourke CJ, Castven D, Pérez-Aguilar B, Becker D, Heilmann-Heimbach S, Odenthal M, Amer W, Schmiel M, Drebber U, Binder H, Ridder DA, Schindeldecker M, Straub BK, Galle PR, Andersen JB, Thorgeirsson SS, Park YN, Marquardt JU. Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis. JCI Insight. 2021;6(17). doi:10.1172/jci.insight.146196
  25. Reich TR, Schwarzenbach C, Vilar JB, Unger S, Mühlhäusler F, Nikolova T, Poplawski A, Baymaz HI, Beli P, Christmann M, Tomicic MT. Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination. Cellular and Molecular Life Sciences. 2021;78(14):5587-5604. doi:10.1007/s00018-021-03864-0
  26. Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han X, Ong JS, Hewitt AW, Segrè AV, Rouhana JM, Hamel AR, Igo RP, Choquet H, Qassim A, Josyula NS, Cooke Bailey JN, Bonnemaijer PWM, Iglesias A, Siggs OM, Young TL, Vitart V, Thiadens AAHJ, Karjalainen J, Uebe S, Melles RB, Nair KS, Luben R, Simcoe M, Amersinghe N, Cree AJ, Hohn R, Poplawski A, Chen LJ, Rong SS, Aung T, Vithana EN, Allingham RR, Brilliant M, Budenz DL, Bailey JNC, Fingert JH, Gaasterland D, Gaasterland T, Haines JL, Hauser M, Lee RK, Lichter PR, Liu Y, Moroi S, Myers J, Pericak-Vance M, Realini A, Rhee D, Richards JE, Ritch R, Schuman JS, Scott WK, Singh K, Sit AJ, Vollrath D, Weinreb RN, Wollstein G, Zack DJ, Sharma S, Martin S, Zhou T, Souzeau E, Landers J, Fitzgerald JT, Mills RA, Craig J, Burdon K, Graham SL, Casson RJ, Goldberg I, White AJ, Healey PR, Mackey DA, Hewitt AW, Shiono M, Misumi K, Kaieda R, Harada H, Minami S, Emi M, Emoto N, Daida H, Miyauchi K, Murakami A, Asai S, Moriyama M, Takahashi Y, Fujioka T, Obara W, Mori S, Ito H, Nagayama S, Miki Y, et al. Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature Communications. 2021;12(1). doi:10.1038/s41467-020-20851-4
  27. Gaonkar KS, Marini F, Rathi KS, Jain P, Zhu Y, Chimicles NA, Brown MA, Naqvi AS, Zhang B, Storm PB, Maris JM, Raman P, Resnick AC, Strauch K, Taroni JN, Rokita JL. annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions. BMC Bioinformatics. 2020;21(1). doi:10.1186/s12859-020-03922-7
  28. Bogucka K, Marini F, Rosigkeit S, Schloeder J, Jonuleit H, David K, Schlackow M, Rajalingam K. ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis. Cancer Gene Therapy. 2020;28(5):359-374. doi:10.1038/s41417-020-00245-w
  29. Marini F, Linke J, Binder H. ideal: an R/Bioconductor package for interactive differential expression analysis. BMC Bioinformatics. 2020;21(1). doi:10.1186/s12859-020-03819-5
  30. Marini F, Scherzinger D, Danckwardt S. TREND-DB—a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation. Nucleic Acids Research. 2020;49(D1):D243-D253. doi:10.1093/nar/gkaa722
  31. Brackmann LK, Poplawski A, Grandt CL, Schwarz H, Hankeln T, Rapp S, Zahnreich S, Galetzka D, Schmitt I, Grad C, Eckhard L, Mirsch J, Blettner M, Scholz-Kreisel P, Hess M, Binder H, Schmidberger H, Marron M. Comparison of time and dose dependent gene expression and affected pathways in primary human fibroblasts after exposure to ionizing radiation. Molecular Medicine. 2020;26(1). doi:10.1186/s10020-020-00203-0
  32. Roewe J, Stavrides G, Strueve M, Sharma A, Marini F, Mann A, Smith SA, Kaya Z, Strobl B, Mueller M, Reinhardt C, Morrissey JH, Bosmann M. Bacterial polyphosphates interfere with the innate host defense to infection. Nature Communications. 2020;11(1). doi:10.1038/s41467-020-17639-x
  33. Soneson C, Marini F, Geier F, Love MI, Stadler MB. ExploreModelMatrix: Interactive exploration for improved understanding of design matrices and linear models in R. F1000Research. 2020;9:512. doi:10.12688/f1000research.24187.1
  34. Hauptmann J, Johann L, Marini F, Kitic M, Colombo E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC, Klein M, Cardoso S, Strauß J, Bolisetty S, Lühder F, Schwaninger M, Binder H, Bechman I, Bopp T, Agarwal A, Soares MP, Regen T, Waisman A. Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrier. Acta Neuropathologica. 2020;140(4):549-567. doi:10.1007/s00401-020-02187-x
  35. Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit S, Grimminger P, Schild H, Rajalingam K. ERK3/MAPK6 controls IL-8 production and chemotaxis. eLife. 2020;9. doi:10.7554/elife.52511
  36. Mohebiany AN, Ramphal NS, Karram K, Di Liberto G, Novkovic T, Klein M, Marini F, Kreutzfeldt M, Härtner F, Lacher SM, Bopp T, Mittmann T, Merkler D, Waisman A. Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology. Cell Reports. 2020;30(5):1585-1597.e6. doi:10.1016/j.celrep.2019.12.097
  37. Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang Y, Klein M, Bittner S, Steffen F, Moos S, Marini F, Gloury R, Kurschus FC, Chao YY, Bertrams W, Sexl V, Schmeck B, Bonetti L, Grusdat M, Lohoff M, Zielinski CE, Zipp F, Kallies A, Brenner D, Berger M, Bopp T, Tackenberg B, Huber M. IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis. Nature Communications. 2019;10(1). doi:10.1038/s41467-019-13731-z
  38. Amezquita RA, Lun ATL, Becht E, Carey VJ, Carpp LN, Geistlinger L, Marini F, Rue-Albrecht K, Risso D, Soneson C, Waldron L, Pagès H, Smith ML, Huber W, Morgan M, Gottardo R, Hicks SC. Orchestrating single-cell analysis with Bioconductor. Nature Methods. 2019;17(2):137-145. doi:10.1038/s41592-019-0654-x
  39. Graf C, Wilgenbus P, Pagel S, Pott J, Marini F, Reyda S, Kitano M, Macher-Göppinger S, Weiler H, Ruf W. Myeloid cell–synthesized coagulation factor X dampens antitumor immunity. Science Immunology. 2019;4(39). doi:10.1126/sciimmunol.aaw8405
  40. Akhtar J, More P, Albrecht S, Marini F, Kaiser W, Kulkarni A, Wojnowski L, Fontaine JF, Andrade-Navarro MA, Silies M, Berger C. TAF-ChIP: an ultra-low input approach for genome-wide chromatin immunoprecipitation assay. Life Science Alliance. 2019;2(4):e201900318. doi:10.26508/lsa.201900318
  41. Marini F, Binder H. pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components. BMC Bioinformatics. 2019;20(1). doi:10.1186/s12859-019-2879-1
  42. Akhtar J, Kreim N, Marini F, Mohana G, Brüne D, Binder H, Roignant JY. Promoter-proximal pausing mediated by the exon junction complex regulates splicing. Nature Communications. 2019;10(1). doi:10.1038/s41467-019-08381-0
  43. Ogorodnikov A, Levin M, Tattikota S, Tokalov S, Hoque M, Scherzinger D, Marini F, Poetsch A, Binder H, Macher-Göppinger S, Probst HC, Tian B, Schaefer M, Lackner KJ, Westermann F, Danckwardt S. Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma. Nature Communications. 2018;9(1). doi:10.1038/s41467-018-07580-5
  44. Nührenberg TG, Cederqvist M, Marini F, Stratz C, Grüning BA, Trenk D, Binder H, Gilsbach R, Neumann FJ, Hein L. Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome. BioMed Research International. 2018;2018:1-9. doi:10.1155/2018/8989252
  45. Haase T, Müller C, Krause J, Röthemeier C, Stenzig J, Kunze S, Waldenberger M, Münzel T, Pfeiffer N, Wild P, Michal M, Marini F, Karakas M, Lackner K, Blankenberg S, Zeller T. Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking. Biomolecules. 2018;8(3):74. doi:10.3390/biom8030074
  46. Rue-Albrecht K, Marini F, Soneson C, Lun ATL. iSEE: Interactive SummarizedExperiment Explorer. F1000Research. 2018;7:741. doi:10.12688/f1000research.14966.1
  47. Goesswein D, Habtemichael N, Gerhold-Ay A, Mazur J, Wünsch D, Knauer SK, Künzel J, Matthias C, Strieth S, Stauber RH. Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers. Scientific Reports. 2018;8(1). doi:10.1038/s41598-018-25512-7
  48. Foerster F, Hess M, Gerhold-Ay A, Marquardt JU, Becker D, Galle PR, Schuppan D, Binder H, Bockamp E. The immune contexture of hepatocellular carcinoma predicts clinical outcome. Scientific Reports. 2018;8(1). doi:10.1038/s41598-018-21937-2
  49. Shen L, Tenzer S, Hess M, Distler U, Tubbe I, Montermann E, Schimmer S, Dittmer U, Grabbe S, Bros M. Friend virus limits adaptive cellular immune responses by imprinting a maturation-resistant and T helper type 2-biased immunophenotype in dendritic cells. Santiago ML, ed. PLOS ONE. 2018;13(2):e0192541. doi:10.1371/journal.pone.0192541
  50. Hess M, Lenz S, Blätte TJ, Bullinger L, Binder H. Partitioned learning of deep Boltzmann machines for SNP data. Hancock J, ed. Bioinformatics. 2017;33(20):3173-3180. doi:10.1093/bioinformatics/btx408
  51. Hahn M, Bürckert JP, Luttenberger CA, Klebow S, Hess M, Al-Maarri M, Vogt M, Reißig S, Hallek M, Wienecke-Baldacchino A, Buch T, Muller CP, Pallasch CP, Wunderlich FT, Waisman A, Hövelmeyer N. Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-κB signaling. Leukemia. 2017;32(1):72-82. doi:10.1038/leu.2017.168
  52. Campos Carrascosa L, Klein M, Kitagawa Y, Lückel C, Marini F, König A, Guralnik A, Raifer H, Hagner-Benes S, Rädler D, Böck A, Kang C, Lohoff M, Garn H, Schaub B, Berberich-Siebelt F, Sakaguchi S, Bopp T, Huber M. Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4. Nature Communications. 2017;8(1). doi:10.1038/ncomms15366
  53. Iglesias AI, der Lee SJ, Bonnemaijer PWM, Höhn R, Nag A, Gharahkhani P, Khawaja AP, Broer L, Foster PJ, Hammond CJ, Hysi PG, Leeuwen EM, MacGregor S, Mackey DA, Mazur J, Nickels S, Uitterlinden AG, Klaver CCW, Amin N, Duijn CM. Haplotype reference consortium panel: Practical implications of imputations with large reference panels. Human Mutation. 2017;38(8):1025-1032. doi:10.1002/humu.23247
  54. Yurugi H, Marini F, Weber C, David K, Zhao Q, Binder H, Désaubry L, Rajalingam K. Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours. Oncogene. 2017;36(33):4778-4789. doi:10.1038/onc.2017.93
  55. de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M, Weng LC, Pool R, Grossmann V, Brody JA, Venturini C, Tanaka T, Rose LM, Oldmeadow C, Mazur J, Basu S, Frånberg M, Yang Q, Ligthart S, Hottenga JJ, Rumley A, Mulas A, de Craen AJM, Grotevendt A, Taylor KD, Delgado GE, Kifley A, Lopez LM, Berentzen TL, Mangino M, Bandinelli S, Morrison AC, Hamsten A, Tofler G, de Maat MPM, Draisma HHM, Lowe GD, Zoledziewska M, Sattar N, Lackner KJ, Völker U, McKnight B, Huang J, Holliday EG, McEvoy MA, Starr JM, Hysi PG, Hernandez DG, Guan W, Rivadeneira F, McArdle WL, Slagboom PE, Zeller T, Psaty BM, Uitterlinden AG, de Geus EJC, Stott DJ, Binder H, Hofman A, Franco OH, Rotter JI, Ferrucci L, Spector TD, Deary IJ, März W, Greinacher A, Wild PS, Cucca F, Boomsma DI, Watkins H, Tang W, Ridker PM, Jukema JW, Scott RJ, Mitchell P, Hansen T, O’Donnell CJ, Smith NL, Strachan DP, Dehghan A. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. Yao YG, ed. PLOS ONE. 2017;12(1):e0167742. doi:10.1371/journal.pone.0167742
  56. Poplawski A, Binder H. Feasibility of sample size calculation for RNA-seq studies. Briefings in Bioinformatics. Published online January 18, 2017:bbw144. doi:10.1093/bib/bbw144
  57. Sennblad B, Basu S, Mazur J, Suchon P, Martinez-Perez A, van Hylckama Vlieg A, Truong V, Li Y, Gådin JR, Tang W, Grossman V, de Haan HG, Handin N, Silveira A, Souto JC, Franco-Cereceda A, Morange PE, Gagnon F, Soria JM, Eriksson P, Hamsten A, Maegdefessel L, Rosendaal FR, Wild P, Folsom AR, Trégouët DA, Sabater-Lleal M. Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels. Human Molecular Genetics. Published online January 4, 2017:ddw401. doi:10.1093/hmg/ddw401
  58. Paret C, Theruvath J, Russo A, Kron B, Malki KE, Lehmann N, Wingerter A, Neu MA, Gerhold-Ay A, Wagner W, Sommer C, Pietsch T, Seidmann L, Faber J. Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy. Oncotarget. 2016;7(50):83378-83391. doi:10.18632/oncotarget.13092
  59. Hafner C, Wu J, Tiboldi A, Hess M, Mitulovic G, Kaun C, Krychtiuk KA, Wojta J, Ullrich R, Tretter EV, Markstaller K, Klein KU. Hyperoxia Induces Inflammation and Cytotoxicity in Human Adult Cardiac Myocytes. Shock. 2017;47(4):436-444. doi:10.1097/shk.0000000000000740
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  64. Tuettenberg A, Hahn SA, Mazur J, Gerhold-Ay A, Scholma J, Marg I, Ulges A, Satoh K, Bopp T, Joore J, Jonuleit H. Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network. Unutmaz D, ed. PLOS ONE. 2016;11(2):e0149193. doi:10.1371/journal.pone.0149193
  65. Feldmeyer B, Mazur J, Beros S, Lerp H, Binder H, Foitzik S. Gene expression patterns underlying parasite‐induced alterations in host behaviour and life history. Molecular Ecology. 2016;25(2):648-660. doi:10.1111/mec.13498
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  71. Schwarz A, Tenzer S, Hackenberg M, Erhart J, Gerhold-Ay A, Mazur J, Kuharev J, Ribeiro JMC, Kotsyfakis M. A Systems Level Analysis Reveals Transcriptomic and Proteomic Complexity in Ixodes Ricinus Midgut and Salivary Glands During Early Attachment and Feeding. Molecular & Cellular Proteomics. 2014;13(10):2725-2735. doi:10.1074/mcp.m114.039289
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